I am a freshly qualified junior doctor trained at the University of Cambridge and an aspiring cardiac surgeon.

Currently, I am undertaking a two year foundation training post in the East of England. I am also involved in researching outcomes in cardiac surgery at the Royal Papworth Hospital and hold several teaching commitments across the University of Cambridge and its colleges, instructing undergraduate natural scientists and medical students in physiology.

I obtained an undergraduate research degree in Physiology, and my project investigated murine models of inherited arrhythmic syndromes and the effects of metabolic derangement on arrhythmogenic substrate formation. This work has since been published in peer-reviewed journals. Extra-curricular interests of mine include distance running, astronomy, and aviation/flight simulators.

CV

Education

Churchill College, University of Cambridge, UK	MB BChir	2015-2021
Churchill College, University of Cambridge, UK	BA (Hons)	2015-2018
The British School in Colombo, Sri Lanka	A Levels (4 A+s)	2014

Research

Publications
For a full list of publications please see this link
Original research
Saadeh K, Chadda KR, Ahmad S, Valli H, Nanthakumar N, Fazmin IT, Edling CE, Huang CLH, Jeevaratnam K. Molecular basis of ventricular arrhythmogenicity in a Pgc-1α deficient murine model. Molecular Genetics and Metabolism Reports. 2021 April. DOI:10.1016/j.ymgmr.2021.100753
Fazmin IT, Rafiq MU, Nashef SA, Ali JM. Inferior outcomes following cardiac surgery in patients with a functioning renal allograft. Interactive CardioVascular and Thoracic Surgery. 2020 September. PMID:33212501. DOI:10.1093/icvts/ivaa245
Saadeh K, Achercouk Z, Fazmin IT, Nantha Kumar N, Salvage SC, Edling CE, Huang CLH, Jeevaratnam K. Protein expression profiles in murine ventricles modeling catecholaminergic polymorphic ventricular tachycardia: effects of genotype and sex. Annals of the New York Academy of Sciences. 2020 Jul 26. PMID 32713021 DOI:10.1111/nyas.14426
Edling CE, Fazmin IT, Saadeh K, Chadda KR, Ahmad S, Valli H, Huang CL, Jeevaratnam K. Molecular basis of arrhythmic substrate in ageing murine peroxisome proliferator-activated receptor gamma coactivator deficient (Pgc-1β-/-) hearts modelling mitochondrial dysfunction. Bioscience reports. 2019 Nov. PMID:31778152. DOI:10.1042/BSR20190403
Edling CE, Fazmin IT, Chadda K, Ahmad S, Valli H, Huang C, Jeevaratnam K. Atrial transcriptional profiles of molecular targets mediating electrophysiological function in ageing and Pgc-1β deficient murine hearts. Frontiers in Physiology. 2019;10:497. PMID:31068841. DOI:10.3389/fphys.2019.00497.
Edling CE, Fazmin IT, Chadda KR, Ahmad S, Valli H, Grace AA, Huang CL, Jeevaratnam K. Ageing in Pgc-1β-/-mice modelling mitochondrial dysfunction induces differential expression of a range of genes regulating ventricular electrophysiology. Bioscience Reports. 2019 Mar 26:BSR20190127. PMID:30914453. DOI:10.1042/BSR20190127.
Review articles
Saadeh K, Nantha Kumar N, Fazmin IT, Edling CE, Jeevaratnam K. Anti-malarial drugs: mechanisms underlying their proarrhythmic effects. British Journal of Pharmacology. 2022 Sep 27. DOI:10.1111/bph.15959. PMID: 36165125.
Nantha Kumar N, Nyatsuro K, Ahmad S, Fazmin IT, Saadeh K, Tse G, Jeevaratnam K. Systematic review of renal denervation for the management of cardiac arrhythmias. Clin Res Cardiol. 2021 Nov 8. DOI:10.1007/s00392-021-01950-8. PMID: 34748053.
Saadeh K, Fazmin IT. Mitochondrial dysfunction increases arrhythmic triggers and substrates; potential anti-arrhythmic pharmacological targets. Frontiers In Cardiovascular Medicine. 2021. DOI:10.3389/fcvm.2021.646932.
Abu-Omar Y, Fazmin IT, Ali JM, Pelletier MP. Minimally invasive mitral valve surgery. Journal of Thoracic Disease. 2020. PMID:33841982. DOI:10.21037/jtd-20-2114
Fazmin IT, Achercouk Z, Edling CE, Said A, Jeevaratnam K. Circulating microRNA as a Biomarker for Coronary Artery Disease. Biomolecules. 2020 Sep 23. PMID:32977454. DOI:10.3390/biom10101354.
Fazmin IT, Huang CL, Jeevaratnam K. Bisphosphonates and atrial fibrillation: revisiting the controversy. Annals of the New York Academy of Sciences. 2020 Mar 24. PMID:32208537 DOI:10.1111/nyas.14332
Chadda KR, Fazmin IT, Ahmad S, Valli H, Edling CE, Huang CL, Jeevaratnam K. Arrhythmogenic mechanisms of obstructive sleep apnea in heart failure patients. Sleep. 2018 Jul 16;41(9):zsy136. PMID:30016501. DOI:10.1093/sleep/zsy136.
Case reports
Fazmin IT, Zhang R, Martin CA. Pleuritic chest pain post catheter ablation procedure. BMJ Heart. 2021. DOI:10.1136/heartjnl-2021-319721. PMID:34521735
Letters
Fazmin IT, Ali JM. Re-exploration and bleeding rates after cardiac surgery can be reduced-The utility of a checklist. J Card Surg. 2020. PMID:33135219 DOI:10.1111/jocs.15142

Presentations
Oral presentations
Fazmin IT, Rafiq MU, Nashef SA, Ali JM. Inferior survival following cardiac surgery in patients with a functioning renal allograft. Cambridge National Cardiology Conference 2020, organised by the Cambridge University Cardiology Society, February 2020, Cambridge, UK
Poster presentations
Fazmin IT, Edling CE, Saadeh K, Chadda KR, Valli H, Ahmad S, Huang CLH, Jeevaratnam K. Transcriptional and protein expression changes associated with pro-arrhythmic phenotypes in ageing and Pgc-1β knockout murine models of mitochondrial dysfunction. 4th EU-CardioRNA Working Group Meeting, February 2020, Maastricht, The Netherlands
Fazmin IT, Zhang RY, Porto A, Divulwewa K, Reddy A, Gonzalez-Panizo J, di Nubila B, Mausa MF, Agarwal S, Begley D, Flynn S, Grace A, Heck P, Mellor G, Virdee M, Martin CA. Improved outcome in ablation of ventricular tachycardia in patients with structural heart disease under general anaesthetic. Heart Rhythm Congress 2019, organised by the British Heart Rhythm Society and Arrhythmia Alliance, October 2019, Birmingham, UK
Fazmin IT, Edling CE, Chadda KR, Ahmad S, Valli H, Huang CLH, Jeevaratnam K. Molecular basis of arrhythmic substrate in ageing, Pgc-1β-deficient, murine hearts modelling mitochondrial dysfunction. Europhysiology 2018, organised by the Physiological Society, September 2018, London, UK Winner, Rob Clarke Silver Award for Undergraduate Research

Teaching experience

University of Cambridge	2018-Present
Undergraduate supervisor
Formal teaching appointment for small group teaching for first-year medical students and second-year natural scientists on course content and exam preparation. Underwent centrally organised training by the University of Cambridge Centre for Teaching and Learning and am accredited for teaching life sciences at the undergraduate level. Courses taught: Medical Sciences Tripos, Part 1A - Homeostasis (Physiology); Natural Sciences Tripos, Part 1B - Physiology. Colleges taught: Churchill College, Girton College, Homerton College, Magdalene College, Trinity College

School of Clinical Medicine, University of Cambridge	2019-Present
Associate clinical supervisor Formal teaching appointment, teaching fourth year Student Doctors clinical examination skills.	2019-2020
Intermediate Clinical Supervisor Ward based teaching aimed at third year pre-clinical medical students to get them comfortable interacting with patients in a clinical setting.	2019-2020
Preparing for Patients B Facilitator Formal teaching appointment, ward based teaching for second year pre-clinical medical students, teaching them communication skills. This was followed by leading a debrief session to reflect on lessons learnt and areas to improve upon.	2019-2020

Prizes and awards

2020	Student Led Teaching Award - Shortlisted, Innovative Teaching Award University of Cambridge
2018	Rob Clark Silver Award for Undergraduate Research The Physiological Society, UK
2017	Biomedical Vacation Scholarship Wellcome Trust
2017	Prize Scholarship Churchill College, University of Cambridge
2017	Medical and veterinary prize Churchill College, University of Cambridge
2014	Best A Level Results The British School in Colombo
2012	Sixth Form Tuition Fee Scholarship The British School in Colombo